Sreetharan Kanthaswamy
Associate Professor, School of Mathematical and Natural Sciences, New College of Interdisciplinary Arts and Sciences
School of Mathematical and Natural Sciences
Arizona State University, West campus
4701 W. Thunderbird Road
Glendale, AZ 85306
Titles
- Senior Global Futures Scientist, Julie Ann Wrigley Global Futures Laboratory
- Associate Professor, School of Mathematical and Natural Sciences, New College of Interdisciplinary Arts and Sciences
- Director, Forensic Science PSM
- Research Geneticist, California National Primate Research Center (CNPRC)
Biography
Sreetharan Kanthaswamy is an associate professor in the School of Mathematical and Natural Sciences at Arizona State University's West campus. He is also a research geneticist at the California National Primate Research Center, University of California, Davis. His research on primate genetics and genomics is centered on the investigation of anthropogenic and natural forces which shape and structure genetic variation of natural and captive animal populations.
His forensic science research is based on the analyses of traces of blood, saliva and hair collected at crime scenes or from civil cases for DNA-typing. To further forensic science and provide educational opportunities for students, his research aims to establish species-specific STRs, SNPs and mtDNA markers for accurate and precise genetic identification and to enhance population genetics databases for each species. Dr Kanthaswamy provides expert witness testimony on human and animal (veterinary) forensic DNA analysis and casework review.
Professor Kanthaswamy obtained his bachelor's degree (with honors) and master's degree in genetics at the University of Malaya, Malaysia. He then completed his doctorate at University of California-Davis, and did his postdoctoral research at the University of Iowa-Carver College of Medicine. Prior to joining ASU in 2015, he was a professor at the Environmental Toxicology Department, University of California-Davis and a visiting associate professor at the California State University, Sacramento Environmental Studies Department.
Education
- PhD, Genetics, University of California-Davis, 2001
- MPhil, Genetics, University of Malaya, 1993
- BSc (with honors), Genetics, University of Malaya, 1990
Expertise
- genomics
- population genetics
- evolutionary genetics
- forensic genetics
- conservation genetics
- wetland conservation and management
External Links
Journal Articles
In Press
Kanthaswamy, S., R. F. Oldt, R. Said, J. Grijalva, A. Falak, A. Falak, A. Jensen, C. Vizor, P. Houghton, S. Bunlungsup, S. Malaivijitnond and D. G. Smith. Partial sequence analyses of Exon 7 of the ABO locus of cynomolgus (Macaca fascicularis and rhesus (M. mulatta macaques: Interdeterminate phenotypes reveal the presence of the O blood group. HLA Immune Response Genetics DOI: 10.1111/tan.13675. (link )
2019
Kanthaswamy, S., R. Oldt, M. Montes and A. Falak. 2019. Comparing two commercial domestic dog (Canis familiaris) STR genotyping kits for forensic identity calculations in a mixed‐breed dog population sample. Animal Genetics 50(1):101-111. DOI: 10.1111/age.12758. (link )
Oldt, R. F., S. Kanthaswamy, M. Montes, L. Schumann, J. Grijalva, S. Bunlungsup, P. Houghton, D. G. Smith and S. Malaivijitnond. 2019. Population genetics of the ABO locus within the rhesus (Macaca mulatta) and cynomolgus (M. fascicularis) macaque hybrid zone. International Journal of Immungenetics 46(1):38-48. DOI: 10.1111/iji.12405. (link )
2018
Almodovar, S., J. Swanson, L. D. Giavedoni, S. Kanthaswamy, C. S. Long, N. F. Voelkel, M. G. Edwards, J. M. Folkvord, E. Connick, S. V. Westmoreland, P. A. Luciw and S. C. Flores. 2018. Lung vascular remodeling, cardiac hypertrophy, and inflammatory cytokines in SHIV nef-infected macaques. Viral Immunology 31(3):206-222. DOI: 10.1089/vim.2017.0051. (link )
Day, G. Q., J. Ng, R. F. Oldt, P. W. Houghton, D. G. Smith and S. Kanthaswamy. 2018. DNA-based determination of ancestry in Cynomolgus Macaques (Macaca fascicularis). Journal of the American Association for Laboratory Animal Science 57(5):432-442(11). DOI: 10.30802/AALAS-JAALAS-17-000147. (link )
Kanthaswamy, S. and K. L. Bales. 2018. Evaluating the genetic status of a closed colony of titi monkeys (Callicebus cupreus) using multigenerational pedigrees. Journal of Medical Primatology 47(2):139-141. DOI: 10.1111/jmp.12331. (link )
Kanthaswamy, S., J. Ng, R. F. Oldt, K. Philippi-Falkenstein and H. M. Kubisch. 2018. SNP‐based genetic characterization of the Tulane National Primate Research Center's conventional and specific pathogen‐free rhesus macaque (Macaca mulatta) populations. Journal of Medical Primatology 47(1):29-34. DOI: 10.1111/jmp.12284. (link )
Kanthaswamy, S., R. F. Oldt, J. Ng, D. G. Smith, M. I. Martinez and C. A. Sariol. 2018. Determination of major histocompatibility class I and class II genetic composition of the Caribbean Primate Center specific pathogen‐free rhesus macaque (Macaca mulatta) colony based on massively parallel sequencing. Journal of Medical Primatology 47(6):379-387. DOI: 10.1111/jmp.12353. (link )
Ng, J., R. F. Oldt and S. Kanthaswamy. 2018. Assessing the FBI’s Native American STR database for random match probability calculations. Legal Medicine 30(Jan):52-55. DOI: 10.1016/j.legalmed.2017.10.012. (link )
2017
Bunlungsup, S., S. Kanthaswamy, R. F. Oldt, D. G. Smith, P. Houghton, Y. Hamada and S. Malaivijitnond. 2017. Genetic analysis of samples from wild populations opens new perspectives on hybridization between long‐tailed (Macaca fascicularis) and rhesus macaques (Macaca mulatta). American Journal of Primatology 79(12):e22726. DOI: 10.1002/ajp.22726. (link )
Kanthaswamy, S., J. Ng, R. F. Oldt, L. Valdivia, P. Houghton and D. G. Smith. 2017. ABO blood group phenotype frequency estimation using molecular phenotyping in rhesus and cynomolgus macaques. HLA Human Response Genetics 90(5):295-299. DOI: 10.1111/tan.13118. (link )
Kanthaswamy, S., R. F. Oldt, J. Ng, A. V. Ruiz-Lambides, E. Maldonado, M. I. Martinez and C. A. Sariol. 2017. Population genetic structure of the Cayo Santiago colony of rhesus macaques (Macaca mulatta). Journal of the American Association for Laboratory Animal Science 56(4):396-401. (link )
Wendt, F. R., J. L. King, N. M. Novroski, J. D. Churchill, J. Ng, R. Oldt, K. L. McCulloh, J. A. Weise, D. G. Smith, S. Kanthaswamy and B. Budowle. 2017. Flanking region variation of ForenSeq™ DNA Signature Prep Kit STR and SNP loci in Yavapai Native Americans. Forensic Science International: Genetics 28(May):146-154. DOI: 10.1016/j.fsigen.2017.02.014. (link )
Zhang, X., S. Kanthaswamy, J. S. Trask, J. Ng, R. F. Oldt, J. L. Mankowski, R. J. Adams and D. G. Smith. 2017. Genetic characterization of a captive colony of pigtailed macaques (Macaca nemestrina). Journal of the American Association for Laboratory Animal Science 56(4):390-395(6). (link )
Zhang, X., Y. Meng, P. Houghton, M. Liu, S. Kanthaswamy, R. Oldt, J. Ng, J. S. Trask, R. Huang, B. Singh, H. Du and D. G. Smith. 2017. Ancestry, Plasmodium cynomolgi prevalence and rhesus macaque admixture in cynomolgus macaques (Macaca fascicularis) bred for export in Chinese breeding farms. Journal of Medical Primatology 46(2):31-41. DOI: 10.1111/jmp.12256. (link )
2016
Hasan, M. K., M. M. Feeroz, L. Jones-Engel, G. A. Engel, S. Akhtar, S. Kanthaswamy and D. G. Smith. 2016. Performing monkeys of Bangladesh: Characterizing their source and genetic variation. Primates 57(2):221-230. DOI: 10.1007/s10329-015-0508-9. (link )
Kanthaswamy, S., J. Ng, J. E. Broatch, J. Short and J. Roberts. 2016. Mitigating Chinese–Indian rhesus macaque (Macaca mulatta) hybridity at the California National Primate Research Center (CNPRC). Journal of Medical Primatology 45(6):333-335. DOI: 10.1111/jmp.12231. (link )
Kanthaswamy, S., J. Ng, R. Hernandez-Pacheco, A. Ruiz-Lambides, E. Maldonado, M. I. Martinez and C. A. Sariol. 2016. The population genetic composition of conventional and SPF colonies of rhesus macaques (Macaca mulatta at the Caribbean Primate Research Center. Journal of the American Association for Laboratory Animal Science 55(2):147-151. (link )
Kanthaswamy, S., J. Ng, R. Hernandez-Pacheco, A. Ruiz-Lambides, E. Maldonado, M. I. Martinez and C. A. Sariol. 2016. The population genetic composition of conventional and SPF colonies of rhesus macaques (Macaca mulatta) at the Caribbean Primate Research Center. Journal of the American Association for Laboratory Animal Science 55(2):147-151. (link )
McCulloh, K. L., J. Ng, R. F. Oldt, J. A. Weise, J. Viray, B. Budowle, D. G. Smith and S. Kanthaswamy. 2016. The genetic structure of native Americans in North America based on the Globalfiler® STRs. Legal Medicine 23(Nov):49-54. DOI: 10.1016/j.legalmed.2016.09.007. (link )
Ng, J., R. F. Oldt, K. L. McCulloh, J. A. Weise, J. Viray, B. Budowle, D. G. Smith and S. Kanthaswamy. 2016. Native American population data based on the Globalfiler® autosomal STR loci. Forensic Science International: Genetics 24(Sep):e12-e13. DOI: 10.1016/j.fsigen.2016.06.014. (link )
Reader, J. R., D. R. Canfield, J. F. Lane, S. Kanthaswamy, A. Ardeshir, A. M. Allen and R. P. Tarara. 2016. Left ventricular hypertrophy in rhesus macaques (Macaca mulatta at the California National Primate Research Center (1992-2014). Comparative Medicine 66(2):162-169. (link )
Wendt, F. R., J. D. Churchill, N. M. Novroski, J. L. King, J. Ng, R. Oldt, K. L. McCulloh, J. A. Weise, D. G. Smith, S. Kanthaswamy and B. Budowle. 2016. Genetic analysis of the Yavapai Native Americans from west-central Arizona using the Illumina MiSeq FGx™ forensic genomics system. Forensic Science International: Genetics 24(Sep):18-23. DOI: 10.1016/j.fsigen.2016.05.008. (link )
Xue, C., M. Raveendran, R. A. Harris, G. L. Fawcett, X. Liu, S. White, M. Dahdouli, D. Rio Deiros, J. E. Below, W. Salerno, L. A. Cox, G. Fan, B. Fergusen, J. Horvath, Z. Johnson, S. Kanthaswamy, H. M. Kubisch, D. Liu, M. Platt, D. G. Smith, B. Sun, E. J. Vallender, F. Wang, R. Wiseman, R. Chen, D. M. Muzny, R. A. Gibbs, F. Yu and J. Rogers. 2016. The population genomics of rhesus macaques (Macaca mulatta) based on whole genome sequences. Genome Research 26:1651-1662. DOI: 10.1101/gr.204255.116. (link )
2015
Below, J. E., M. Raveendran, R. A. Harris, C. Xue, B. Ferguson, S. Kanthaswamy, D. G. Smith, C. J. Jolly, J. Phillips-Conroy, D. Muzny, R. Gibbs, F. Yu and J. Rogers. 2015. Abstract 11: IBD estimation, segmental sharing detection, and pedigree reconstruction in non‐human primates. Genetic Epidemiology 39(7):532-533. DOI: 10.1002/gepi.21916. (link )
Kanthaswamy, S. 2015. Review: Domestic animal forensic genetics – biological evidence, genetic markers, analytical approaches and challenges. Animal Genetics 46(5):473-484. DOI: 10.1111/age.12335. (link )
McIlmoyle, G., J. S. Trask, E. Kinnaly, J. Ng, D. G. Smith and S. Kanthaswamy. 2015. CpG methylation in the serotonin transporter gene promoter region is not associated with age or social rank of male rhesus macaques (Macaca mulatta). Journal of Nature and Science 1(4):e72. (link )
Mendoza, A., J. Ng, K. L. Bales, S. P. Mendoza, D. A. George, D. G. Smith and S. Kanthaswamy. 2015. Population genetics of the California National Primate Research Center’s (CNPRC) captive Callicebus cupreus colony. Primates 56(1):37-44. DOI: 10.1007/s10329-014-0446-y. (link )
Ng, J., J. N. Fass, B. Durbin-Johnson, D. G. Smith and S. Kanthaswamy. 2015. Identifying rhesus macaque gene orthologs using heterospecific human CNV probes. Genomics Data 6(Dec):202-207. DOI: 10.1016/j.gdata.2015.09.016. (link )
Ng, J., J. S. Trask, P. Houghton, D. G. Smith and S. Kanthaswamy. 2015. Use of genome-wide heterospecific single-nucleotide polymorphisms to estimate linkage disequilibrium in rhesus and cynomolgus macaques. Comparative Medicine 65(1):62-69. (link )
Ng, J., J. S. Trask, D. G. Smith and S. Kanthaswamy. 2015. Heterospecific SNP diversity in humans and rhesus macaque (Macaca mulatta). Journal of Medical Primatology 44(4):194-201. DOI: 10.1111/jmp.12174. (link )
Perez, W. A., J. Ng, R. Oldt, W. M. Green, E. Panacek and S. Kanthaswamy. 2015. Changes in yield of contact DNA over time after a physical assault. Journal of Forensic Research 6(1):253. DOI: 10.4172/2157-7145.1000253. (link )
2014
Hasan, M. K., M. M. Feeroz, L. Jones-Engel, G. A. Engel, S. Kanthaswamy and D. G. Smith. 2014. Diversity and molecular phylogeny of mitochondrial DNA of rhesus macaques (Macaca mulatta) in Bangladesh. American Journal of Primatology 76(11):1094-1104. DOI: 10.1002/ajp.22296. (link )
Kanthaswamy, S., H. A. Elfenbein, A. Ardeshir, J. Ng, D. Hyde, D. G. Smith and N. Lerche. 2014. Familial aggregation of chronic diarrhea disease (CDD) in rhesus macaques (Macaca mulatta). American Journal of Primatology 76(3):262-270. DOI: 10.1002/ajp.22230. (link )
Kanthaswamy, S., Z. Johnson, J. S. Trask, D. G. Smith, R. Ramakrishnan, J. Bahk, J. Ng, R. Wiseman, H. M. Kubisch, E. J. Vallender, J. Rogers and B. Ferguson. 2014. Development and validation of a SNP-based assay for inferring the genetic ancestry of rhesus macaques (Macaca mulatta). American Journal of Primatology 76(11):1105-1113. DOI: 10.1002/ajp.22290. (link )
Kanthaswamy, S. and D. G. Smith. 2014. Genetic and ethnohistoric evidence suggest current Native American population datasets in the FBI's CODIS database are not sufficiently representative. Forensic Science International: Genetics 13:e13-e15. DOI: 10.1016/j.fsigen.2014.05.006. (link )
Kanthaswamy, S., R. Reader, R. Tarara, K. Oslund, M. Allen, J. Ng, C. Grinberg, D. Hyde, D. G. Smith and N. Lerche. 2014. Large-scale pedigree analysis leads to evidence for founder effects of hypertrophic cardiomyopathy in rhesus macaques (Macaca mulatta). Journal of Medical Primatology 43(4):288-291. DOI: 10.1111/jmp.12127. (link )
Ng, J., J. S. Trask, A. Premasuthan and S. Kanthaswamy. 2014. A nuclear DNA-based xpecies determination and DNA quantification assay for common poultry species. Journal of Food Science and Technology 51(12):4060-4065. DOI: 10.1007/s13197-012-0893-7. (link )
Nikzad, S., S. G. Tan, C. Y. Seok Yien, J. Ng, R. Khan, J. J. Rovie-Ryan, A. Valdiani, P. Khajeaian and S. Kanthaswamy. 2014. Genetic diversity and population structure of long-tailed macaque (Macaca fascicularis) populations in Peninsular Malaysia. Journal of Medical Primatology 43(6):433-444. DOI: 10.1111/jmp.12130. (link )
Ross, C. T., J. A. Weise, S. Bonnar, D. Nolin, J. S. Trask, D. G. Smith, B. Ferguson, J. Ha, H. M. Kubisch, A. Vinson and S. Kanthaswamy. 2014. An empirical comparison of short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) for relatedness estimation in Chinese rhesus macaques (Macaca mulatta). American Journal of Primatology 76(4):313-324. DOI: 10.1002/ajp.22235. (link )
Smith, D. G., J. Ng, D. A. George, J. S. Trask, P. Houghton, B. Singh, J. Villano and S. Kanthaswamy. 2014. A genetic comparison of two alleged subspecies of Philippine cynomolgus macaques. American Journal of Physical Anthropology 155(1):136-148. DOI: 10.1002/ajpa.22564. (link )
Williams, S., E. Panacek, W. M. Green, S. Kanthaswamy, C. Hopkins and C. Calloway. 2014. Recovery of salivary DNA from the skin after showering. Forensic Science, Medicine, and Pathology 11(1):29-34. DOI: 10.1007/s12024-014-9635-7. (link )
2013
Jiang, J., S. Kanthaswamy and J. P. Capitanio. 2013. Degree of Chinese ancestry affects behavioral characteristics of infant rhesus macaques (Macaca mulatta). Journal of Medical Primatology 42(1):20-27. DOI: 10.1111/jmp.12026. (link )
Johnson, C. E., A. Premasuthan, J. S. Trask and S. Kanthaswamy. 2013. Species identification of Cannabis sativa seeds using real-time quantitative PCR (qPCR).. Journal of Forensic Sciences 58(2):486-490. DOI: 10.1111/1556-4029.12055. (link )
Kanthaswamy, S., J. Ng, C. T. Ross, J. S. Trask, D. G. Smith, V. S. Buffalo, J. N. Fass and D. Lin. 2013. Identifying human-rhesus macaque gene orthologs using heterospecific SNP probes. Genomics 101(1):30-37. DOI: 10.1016/j.ygeno.2012.09.001. (link )
Kanthaswamy, S., J. Ng, J. S. Trask, D. A. George, A. J. Kou, L. N. Hoffman, T. B. Doherty, P. Houghton and D. G. Smith. 2013. The genetic composition of cynomolgus macaque (Macaca fascicularis) populations used in biomedical research. Journal of Medical Primatology 42(3):120-131. DOI: 10.1111/jmp.12043. (link )
Sandoval, M. P., J. Ng, W. M. Green, E. Panacek and S. Kanthaswamy. 2013. Yield of male contact DNA evidence in an assault simulation model. Journal of Forensic Research T1:002. DOI: 10.4172/2157-7145.T1-002. (link )
Sethi, V., E. Panacek, W. M. Green, J. Ng and S. Kanthaswamy. 2013. Yield of male touch DNA from fabrics in an assault model. Journal of Forensic Research T1:001. DOI: 10.4172/2157-7145.T1-001. (link )
Trask, J. S., W. T. Garnica, D. G. Smith, P. Houghton, N. Lerche and S. Kanthaswamy. 2013. Single nucleotide polymorphisms reveal patterns of allele sharing across the species boundary between rhesus (Macaca mulatta) and cynomolgus (M. fascicularis) macaques. American Journal of Primatology 75(2):135-144. DOI: 10.1002/ajp.22091. (link )
Trask, J. S., D. George, P. Houghton, S. Kanthaswamy and D. G. Smith. 2013. Population and landscape genetics of an introduced species (M. fascicularis) on the Island of Mauritius. PLOS One 8(1):e53001. DOI: 10.1371/journal.pone.0053001. (link )
2012
Kanthaswamy, S., J. Ng, M. C. T. Penedo, T. Ward, D. G. Smith and J. C. Ha. 2012. Population genetics of the Washington National Primate Research Center’s (WaNPRC) captive pigtailed macaque (Macaca nemestrina) population. American Journal of Primatology 74(11):1017-1027. DOI: 10.1002/ajp.22055. (link )
Kanthaswamy, S., J. S. Trask, C. T. Ross, A. Kou, P. Houghton, D. G. Smith and N. Lerche. 2012. A large-scale SNP-based genomic admixture analysis of the captive rhesus macaque colony at the California National Primate Research Center. American Journal of Primatology 74(8):747-757. DOI: 10.1002/ajp.22025. (link )
Premasuthan, A., J. Ng, S. Kanthaswamy, J. S. Trask, P. Houghton, T. Farkas, K. Sestak and D. G. Smith. 2012. Molecular ABO phenotyping in cynomolgus macaques using real-time quantitative PCR. Tissue Antigens: Immune Responsive Antigens 80(4):363-367. DOI: 10.1111/j.1399-0039.2012.01935.x. (link )
Book Chapters
2016
Oldt, R., J. Ng and S. Kanthaswamy. 2016. Chapter 19: The application of forensic animal DNA analysis in criminal and civil investigations. Pp. 473-491 In: Amorim, A. and B. Budowle eds., Handbook of Forensic Genetics: Biodiversity and Heredity in Civil and Criminal Investigation. Vol 2. World Scientific. ISBN: 978-1-78634-077-1.
2014
Menotti-Raymond, M. A., V. A. David, S. J. O'Brien, S. Kanthaswamy, P. Projic, V. Skaro, G. Lauc and A. Linacre. 2014. Forensic animal DNA analysis. Pp. 317-352 In: Primorac, D. and M. Schanfield eds., Forensic DNA Applications: An Interdisciplinary Perspective. CRC Press. ISBN: 978-1466580220.